Aeneas and Ferris
Aeneas and Ferris was a much-loved series by K. Michael Wilcox from the early days of the LNH, focusing on Ferris Alejandro Jones, AKA Deductive Logic Man, and his friendship with immortal mad scientist/"villain" Aeneas Boddy.
Plot
After the events of You Only Live Two or Three Thousand Times, Tops!, the twosome move into a suburban mansion. There, they face a number of strange menaces, such as Gremlins, sentient cockroaches (which Aeneas himself created), and, of course, the neighbors. However, the series focuses on Aeneas and Ferris's heartfelt, complex, often wacky relationship.
Where to Read
Aeneas and Ferris can be read on the Eyrie Archive over here, or on K.M. Wilcox's old website.
Legacy
Aeneas and Ferris spun off The Aeneas Boddy Chronicles and Vulture Team Clooless. It's also, in a somewhat distorted form, a highly popular TV series on Earth-20.